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Transcription factors are members of the proteome as well as regulome. TFs work alone or with other proteins in a complex, by promoting (as an activator), or blocking (as a repressor) the recruitment of RNA polymerase (the enzyme that performs the transcription of genetic information from DNA to RNA) to specific genes.
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Apr 15, 2022 · Characterization of a Salmonella Transcription Factor-DNA Complex and Identification of the Inducer by Native Mass Spectrometry. J Mol Biol ...
New insights into protein–DNA binding specificity from hydrogen ...
www.ncbi.nlm.nih.gov › PMC6868434
Oct 30, 2019 · Based on these observations, we developed a machine learning-based SVM (Support Vector Machine) model for TF (transcription factor)–DNA complex ...
Jan 3, 2021 · Once RNA polymerase has been activated, it will move away from the transcription factor-DNA complex. The DNA bound transcription factor can ...
Feb 25, 2019 · The focus of this project is to model transcription factor-DNA complex structures. Computational docking, by filling the gap in the complex ...
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